This issue with running Frescobaldi on MacOS X must be one of the most long-running among threads of this list. Why can't some of you Mac users please take your responsibility for the community, and see to that a working distribution gets created, from which everybody (with Macs) can benefit, with all the tweaks and dependencies, and then donate this for download from the official Frescobaldi-site. I'd love to be able to recommend a number of friends of mine, sadly (for them) with Apple boxes, to take a look at Frescobaldi, but given the state of affairs here this is simply not possible at the moment. Of course it is easier to do this in, e.g., a Linux platform, but I just can't imagine that it would be that impossible for Macs as is suggested by all these howtos, neither of which seems to work for everybody.
Kind regards /Christian