Is it dangerous to run guix home/system reconfigure from an uninstalled / development Guix profile?

[Nicolas Graves]

When I develop for RDE, I'd like to be able to see the result on a real
system quicker. The bootleneck here is the compilation of a new guix,
whereas I have one readily available in my development directory.

I wonder if there are any hazards to using a development version of Guix
to update one's home/system profile (other than potentially loosing the
repo/commit and not being able to go back to the same state) ?

-- 
Best regards,
Nicolas Graves